Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC HY-129943 50mg Medchemexpress, Benzothiohydrazide CAS:20605-40-7 Purity:>98%
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Medchemexpress, HY-129943 50mg Benzothiohydrazide CAS:20605-40-7 Benzothiohydrazide is an analogue of anti–tubercular agent Isoniazid. Benzothiohydrazide exhibits anti–tubercular activity, with MICs of 132 μM and 264 μM for M. tuberculosis wild type (H37Rv) and clinical mutant strains (IC1 and IC2). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Cayman Chemical Centrinone, Purity: ≥95%, CAS: 1798871-30-3, 1 mg
A Plk4 inhibitor (Ki = 0.16 nM); >1,100- and >2,800-fold selective for Plk4 over Aurora A and Aurora B kinases, respectively, and a panel of 442 kinases at 100 nM; depletes centrosomes and induces apoptosis in HeLa cells at 125 nM
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Medchemexpress LLC MIG/CXCL9 Human HE 20ug
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CXCL9 also known as MIG is one member of the ELR-negative CXC chemokine subfamily and can be induced by IFN- CXCL9 binds to its receptor CXCR3 and can recruit CXCR3 cells such as effector T cells regulatory T cells (Tregs) and CD8 cytotoxic T cells CXCL9 is involved in immunoregulatory and inflammatory processes but it also play a key role in tumor growth angiogenesis and metastasis[1][2] MIG/CXCL9 Protein Human (HEK293 His) is produced in HEK293 cells with six C-Terminal His-tags It consists of 103 amino acids (T23-T125)
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Cayman Chemical ANTIBODY eCF309 500ug
A selective inhibitor of mTOR (IC50 = 15 nM in vitro and in cells)
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Apexbio Technology LLC BMS-708163 (Avagacestat) 1146699-66-2 50mg
BMS-708163 (Avagacestat CAS 1146699-66-2) is an orally bioavailable small-molecule inhibitor selectively targeting -secretase an enzyme responsible for amyloid precursor protein (APP) cleavage into neurotoxic amyloid-beta (A ) species associated with Alzheimer s disease pathology It demonstrates potent inhibitory activity (IC50 0 3 nM) effectively reducing A 40 and A 42 production in vitro in H4-8Sw cells Relative selectivity testing indicates a substantially lower inhibitory effect (approximately 190-fold weaker) toward Notch signaling compared to APP processing In animal models oral administration significantly reduces A levels in plasma cerebrospinal fluid and brain tissues underpinning its application in Alzheimer s disease research
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Medchemexpress LLC Oct-1-en-3-ol | 3391-86-4 | 99.89% | 128.22 | 1 ML
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Oct-1-en-3-ol is a fatty acid fragrant and a self-stimulating oxylipin messenger. It acts as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. It can also cause dopamine neuron degeneration by disrupting dopamine handling.
- Fatty acid fragrant
- Self-stimulating oxylipin messenger
- Signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions
- Causes dopamine neuron degeneration through disruption of dopamine handling
- Appearance: liquid
- Color: colorless to light yellow
- Initial source: plants, microorganisms
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Apexbio Technology LLC DY131 95167-41-2 10mg
DY131 (95167-41-2) is a small-molecule agonist targeting the estrogen-related receptors ERR and ERR It is designed to selectively activate these orphan nuclear receptors thereby regulating estrogen-independent transcriptional pathways DY131 exerts its biological activity primarily through receptor-mediated activation of ERR and preferentially ERR with minimal effect on ERR In cell-based assays DY131 demonstrates moderate to strong agonist activity toward ERR / at low micromolar concentrations Based on these pharmacological properties DY131 holds research potential in investigating ERR-mediated transcriptional responses receptor selectivity and gene regulation particularly in prostate epithelial biology and oncology studies
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Medchemexpress LLC CD94 Human HEK293 10ug
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CD94 protein is a key immune receptor for self-non-self discrimination It forms a complex with KLRC1 or KLRC2 on lymphocyte subsets and recognizes HLA-E loaded with self-peptides It allows cytotoxic cells to monitor MHC class I expression and promote self-tolerance CD94 Protein Human (HEK293 His) is the recombinant human-derived CD94 protein expressed by HEK293 with N-6 His labeled tag
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Medchemexpress LLC 4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide | 1191951-57-1 | 98.1% | 100 MG
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PHT-427 is a small-molecule research inhibitor that binds the pleckstrin homology (PH) domain of Akt and inhibits PDPK1. It is used in preclinical signaling studies with reported Kis of 2.7 μM (Akt PH domain) and 5.2 μM (PDPK1); supplied as a white to off-white solid with high purity for laboratory research use only.
- Inhibits the pleckstrin homology (PH) domain of Akt and PDPK1.
- Reported Ki values of 2.7 μM (Akt PH domain) and 5.2 μM (PDPK1).
- High purity (≈98.1%) suitable for research applications.
- Solid, white to off-white appearance for standard handling.
- Supplied in defined milligram quantities for dosing and formulation studies.
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Cayman Chemical MitoB-d15, Purity: ≥99% deuterated forms (d1-d15), 10 mg
An internal standard for the quantification of MitoB by GC- or LC-MS
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Medchemexpress LLC H4R ANTAGONIST 2 1 mg
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H4R ANTAGONIST 2 1MG
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Medchemexpress LLC NOX2-IN-2 DITFA 5 mg
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NOX2-IN-2 DITFA 5MG
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Medchemexpress LLC STING-IN-7 5 mg
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STING-IN-7 5MG
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Medchemexpress LLC NF- ACTIVATOR 2 100 mg
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NF- ACTIVATOR 2 100MG
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Medchemexpress LLC STING AGONIST-16 100 mg
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STING AGONIST-16 100MG
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